Henry Lik-Yuen Chan Selected Research

RO7062931

10/2021

Clinical Study of Single-Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B.

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Henry Lik-Yuen Chan Research Topics

Disease

79	Chronic Hepatitis B 03/2022 - 02/2002
49	Fibrosis (Cirrhosis) 11/2022 - 02/2002
29	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2008
25	Non-alcoholic Fatty Liver Disease 01/2022 - 09/2006
23	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 05/2002
20	Infections 01/2022 - 05/2002
16	Hepatitis B 01/2021 - 06/2004
13	Liver Diseases (Liver Disease) 01/2022 - 10/2002
11	Neoplasms (Cancer) 01/2021 - 05/2006
10	Hepatitis 01/2021 - 06/2004
6	Fatty Liver 01/2020 - 12/2011
5	Chronic Hepatitis C 09/2019 - 12/2010
4	COVID-19 06/2021 - 01/2020
4	Diabetes Mellitus 01/2021 - 09/2006
4	Hemorrhage 01/2021 - 08/2009
4	End Stage Liver Disease 09/2020 - 10/2005
4	Liver Failure 01/2020 - 06/2004
3	Alcoholic Fatty Liver 09/2020 - 06/2012
3	Body Weight (Weight, Body) 12/2018 - 02/2005
3	Ascites 11/2018 - 10/2009
3	Hypertriglyceridemia 01/2017 - 06/2008
2	Hepatitis C 10/2021 - 01/2020
2	Obesity 10/2021 - 09/2015
2	Acidosis 09/2021 - 01/2015
2	Chronic Renal Insufficiency 09/2021 - 11/2018
2	Hypertension (High Blood Pressure) 04/2021 - 10/2017
2	Liver Neoplasms (Liver Cancer) 12/2020 - 01/2020
2	Weight Loss (Weight Reduction) 12/2018 - 01/2016
2	Peritonitis 11/2018 - 10/2009
2	Hepatic Encephalopathy 11/2018 - 02/2011
2	Insulin Resistance 09/2015 - 01/2010
2	Jaundice (Icterus) 02/2011 - 07/2009
2	Massive Hepatic Necrosis 01/2011 - 10/2002
2	Carcinogenesis 01/2011 - 01/2006
2	Hypoadiponectinemia 06/2008 - 09/2006
1	Overweight 10/2021
1	Type 2 Diabetes Mellitus (MODY) 09/2021

Drug/Important Bio-Agent (IBA)

33	Hepatitis B e AntigensIBA 02/2021 - 02/2002
30	DNA (Deoxyribonucleic Acid)IBA 02/2021 - 02/2002
27	Antiviral Agents (Antivirals)IBA 03/2022 - 06/2005
24	Alanine Transaminase (SGPT)IBA 10/2021 - 02/2005
20	Hepatitis B Surface Antigens (HBsAg)FDA Link 10/2021 - 05/2002
13	entecavir FDA Link 09/2020 - 02/2011
13	Lamivudine (Epivir)FDA Link 11/2019 - 10/2002
12	Tenofovir (Viread)FDA Link 01/2022 - 01/2010
9	Biomarkers (Surrogate Marker)IBA 03/2022 - 01/2006
8	Triglycerides (Triacylglycerol)IBA 10/2021 - 03/2012
7	Protons (Proton)IBA 12/2018 - 03/2012
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2022 - 02/2010
6	AlbuminsIBA 01/2022 - 07/2008
6	BilirubinIBA 10/2021 - 10/2002
6	AntigensIBA 01/2021 - 10/2016
6	InterferonsIBA 01/2018 - 02/2005
5	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 06/2008
4	Ribavirin (Virazole)FDA LinkGeneric 10/2021 - 12/2010
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2006
4	Serum AlbuminIBA 12/2017 - 03/2005
4	Keratin-18 (Keratin 18)IBA 01/2017 - 07/2010
4	AdiponectinIBA 07/2010 - 09/2006
3	tenofovir alafenamideIBA 01/2022 - 06/2018
3	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021 - 01/2019
3	Pharmaceutical PreparationsIBA 04/2020 - 01/2012
3	peginterferon alfa-2a (Pegasys)FDA Link 01/2019 - 12/2014
3	Phospholipases (Phospholipase)IBA 09/2015 - 01/2015
3	Interleukin-6 (Interleukin 6)IBA 07/2010 - 06/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2010 - 09/2006
2	ProdrugsIBA 01/2022 - 06/2018
2	Ritonavir (Norvir)FDA Link 10/2021 - 06/2017
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 08/2009
2	Prednisolone (Predate)FDA LinkGeneric 01/2020 - 01/2019
2	CreatinineIBA 12/2017 - 01/2017
2	CholesterolIBA 12/2017 - 01/2015
2	Biological ProductsIBA 04/2016 - 01/2011
2	hydroxide ionIBA 11/2015 - 04/2015
2	Vitamin D FDA LinkGeneric 11/2015 - 04/2015
2	nasIBA 09/2015 - 04/2015
2	Trans-Activators (Trans-Acting Factor)IBA 01/2011 - 05/2006
2	LeptinIBA 07/2010 - 09/2006
2	peginterferon alfa-2b (Pegintron)FDA Link 06/2010 - 12/2007
2	AdipokinesIBA 01/2010 - 09/2006
2	NucleotidesIBA 06/2008 - 03/2006
2	Interferon-alpha2bIBA 01/2008 - 02/2005
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022
1	Urea (Carbamide)FDA LinkGeneric 01/2022
1	Lopinavir FDA Link 10/2021
1	OligonucleotidesIBA 10/2021
1	RO7062931IBA 10/2021
1	Bicarbonates (Hydrogen Carbonate)IBA 09/2021
1	Lactic Acid (Lactate)FDA LinkGeneric 09/2021
1	Metformin (Glucophage)FDA LinkGeneric 09/2021
1	Alanine (L-Alanine)FDA Link 06/2021
1	TransferasesIBA 06/2021
1	CollagenIBA 01/2021
1	Complement C3 (C3 Complement)IBA 01/2021

Therapy/Procedure

29	Therapeutics 01/2021 - 02/2005
12	Liver Transplantation 09/2020 - 10/2002
2	Hepatectomy 02/2017 - 05/2013
2	Aftercare (After-Treatment) 12/2014 - 07/2009
1	Artificial Respiration (Mechanical Ventilation) 04/2021
1	Immunotherapy 01/2021